Based on Disney's animated series Kim Possible, Team Possible follows Kim and Ron Stoppable as they battle villains, including Senor Senor, Monkey Fist, and Dr. Drakken. During the game, you can switch between Kim and Ron, and you can use their unique gadgets to complete objectives. Kim Possible 3: Team Possible features single- and multiplayer modes, as well as collectible trading cards and unlockable minigames.

Kim returns to battle fiendish villains once again, but this time she's got help in the form of her klutzy partner, Ron Stoppable. Together the pair work as a team to take on Monkey Fist, Senior Senior Sr. and Jr., and of course, the ever-incompetent Dr. Drakken, as they try to work out who stole Kim's grandmother's photo album.